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1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC, EDAC or EDCI) is a water-soluble carbodiimide usually handled as the hydrochloride. [1] It is typically employed in the 4.0-6.0 pH range. It is generally used as a carboxyl activating agent for the coupling of primary amines to yield amide bonds.
In chemistry, aminolysis (/am·i·nol·y·sis/) is any chemical reaction in which a molecule is lysed (split into two parts) by reacting with ammonia (NH 3) or an amine. [1] The case where the reaction involves ammonia may be more specifically referred to as ammonolysis .
In chemistry, ammonolysis (/am·mo·nol·y·sis/) is the process of splitting ammonia into + +. [1] Ammonolysis reactions can be conducted with organic compounds to produce amines (molecules containing a nitrogen atom with a lone pair, :N), [2] or with inorganic compounds to produce nitrides.
5-Methylcytosine (see first Figure) is a methylated form of the DNA base cytosine (C) that often regulates gene transcription and has several other functions in the genome. [1] DNA methylation is the addition of a methyl group to the DNA that happens at cytosine. The image shows a cytosine single ring base and a methyl group added on to the 5 ...
Conversely, the related carbodiimide 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) is often used for solution-phase peptide couplings as its urea byproduct can be removed by washing during aqueous work-up. [11] HOBt HOAt Neighbouring group effect of HOAt. Carbodiimide activation opens the possibility for racemization of the activated ...
β-Alanine ethyl ester is the ethyl ester which hydrolyses within the body to form β-alanine. [4] It is produced industrially by the reaction of ammonia with β-propiolactone. [5] Sources for β-alanine includes pyrimidine catabolism of cytosine and uracil.
One example is Kapton where the repeat unit consists of two imide groups derived from aromatic tetracarboxylic acids. [3] Another example of polyimides is the polyglutarimide typically made from polymethylmethacrylate (PMMA) and ammonia or a primary amine by aminolysis and cyclization of the PMMA at high temperature and pressure, typically in ...
An example of a solvolysis reaction is the reaction of a triglyceride with a simple alcohol such as methanol or ethanol to give the methyl or ethyl esters of the fatty acid, as well as glycerol. This reaction is more commonly known as a transesterification reaction due to the exchange of the alcohol fragments.