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  2. Seizure threshold - Wikipedia

    en.wikipedia.org/wiki/Seizure_threshold

    The term seizure threshold is used to describe the balance between excitatory (glutaminergic) and inhibitory (GABA-ergic) forces in the brain which affect how susceptible a person is to seizures. Those diagnosed with epilepsy or certain other neurological conditions are more vulnerable to seizures if the threshold is reduced, and should be ...

  3. Methadone - Wikipedia

    en.wikipedia.org/wiki/Methadone

    Methadone has been shown to reduce neuropathic pain in rat models, primarily through NMDA receptor antagonism. [ citation needed ] NMDA antagonists such as dextromethorphan , ketamine , tiletamine and ibogaine are being studied for their role in decreasing the development of tolerance to opioids and as possible for eliminating addiction ...

  4. Epilepsy in animals - Wikipedia

    en.wikipedia.org/wiki/Epilepsy_in_animals

    A bottle of veterinary pharmaceutical potassium bromide oral solution used in dogs, primarily as an antiepileptic (to stop seizures) [3] In dogs, epilepsy is often an inherited condition. The incidence of epilepsy/seizures in the general dog population is estimated to be between 0.5% and 5.7%. [4]

  5. Kindling model of epilepsy - Wikipedia

    en.wikipedia.org/wiki/Kindling_model_of_epilepsy

    A seizure may increase the likelihood that more seizures will occur; an old saying in epilepsy research is "seizures beget seizures". [1] Repeated stimulation "lowers the threshold" for more seizures to occur. [4] The brains of experimental animals are repeatedly stimulated, usually with electricity, to induce the seizures. [1]

  6. 7 Alternatives to Chemotherapy for Lymphoma in Dogs - AOL

    www.aol.com/7-alternatives-chemotherapy-lymphoma...

    1. Ketogenic Diet. Cancer cells rely on glucose for energy to grow. The ketogenic diet is a way to provide an alternative energy source to normal cells in the dog's body while starving the cancer ...

  7. Kindling (sedative–hypnotic withdrawal) - Wikipedia

    en.wikipedia.org/wiki/Kindling_(sedative...

    Individuals who have had more withdrawal episodes are at an increased risk of very severe withdrawal symptoms, up to and including seizures and death. Long-term activation of the GABA receptor by sedative–hypnotic drugs causes chronic GABA receptor downregulation as well as glutamate overactivity, which can lead to drug and neurotransmitter ...

  8. Watch this dog help his epileptic owner during a seizure - AOL

    www.aol.com/lifestyle/2015-08-28-watch-this-dog...

    Not only are dogs an adorable companion but they can also be a major help when we are going through a difficult time. Puppies have been trained to use their senses to spot seizures in epileptic ...

  9. Opioid agonist therapy - Wikipedia

    en.wikipedia.org/wiki/Opioid_agonist_therapy

    Opioid agonist therapy (OAT) is a treatment in which prescribed opioid agonists are given to patients who live with Opioid use disorder (OUD). [1] In the case of methadone maintenance treatment (MMT), methadone is used to treat dependence on heroin or other opioids, and is administered on an ongoing basis.