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Zonisamide, sold under the brand name Zonegran among others, is a medication used to treat the symptoms of epilepsy and Parkinson's disease. [ 6 ] [ 7 ] Chemically it is a sulfonamide .
Lacosamide has a K d value just under 5 μM and a B max of about 200 pM/mg. [34] The volume of distribution (V d) of lacosamide in plasma is 0.6 L/kg, which is close to the total volume of water. Lacosamide is ampiphilic and is thus hydrophilic while also lipophilic enough to cross the blood-brain barrier. [35]
Therefore, almost all new epilepsy drugs are initially approved only as adjunctive (add-on) therapies. Patients whose epilepsy is uncontrolled by their medication (i.e., it is refractory to treatment) are selected to see if supplementing the medication with the new drug leads to an improvement in seizure control.
Other side effects which are less frequent but still clinically significant include auditory and visual hallucinations, thoughts of suicide, acute kidney failure, atrial fibrillation, cardiovascular accident, sepsis, new or worsening depression, paranoia, disorientation, meningitis, and seizures.
The risks of using high-strength minoxidil include an increased likelihood of side effects. When using it as a topical solution, side effects of minoxidil may include: Skin irritation. Itching ...
Puppies, elderly dogs, and those with diabetes or weight issues should eat potatoes sparingly, as the starch can lead to blood sugar spikes and weight gain." You Might Also Like 15 Best Denim ...
Again, this isn't a common side effect. But if you’re experiencing negative mood or personality changes (or any other Ozempic side effects ), talk to your doctor ASAP, say both experts.
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