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EndoStim therapy directly targets the weak lower esophageal sphincter (LES) muscle, without altering anatomy or using mechanical constraints. EndoStim's proprietary technology uses functional electrical stimulation (a type of neuromodulation) to restore esophageal function, thereby reducing GERD symptoms.
There are several classes of drugs for acid-related disorders, such as dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD), or laryngopharyngeal reflux. The World Health Organization gives drugs in these classes the categorization code ATC code A02.
Linaprazan is an experimental drug for the treatment of gastroesophageal reflux disease (GERD). Unlike the proton-pump inhibitors (PPIs) which are typically used to treat GERD, linaprazan is a potassium-competitive acid blocker (P-CAB). [1] [2] Linaprazan was developed by AstraZeneca, but it was not successful in clinical trials. [3]
The primary medications used for GERD are proton-pump inhibitors, H 2 receptor blockers and antacids with or without alginic acid. [9] The use of acid suppression therapy is a common response to GERD symptoms and many people get more of this kind of treatment than their case merits.
There are no specific symptoms although symptoms of GERD may be present for years prior as it is associated with a 10–15% risk of Barrett's esophagus. [22] Risk factors include chronic GERD for more than 5 years, being age 50 or older, being non-Hispanic white, being male, having a family history of this disorder, belly fat , and a history of ...
Calcium carbonate antacid tablets. An antacid is a substance which neutralizes stomach acidity and is used to relieve heartburn, indigestion, or an upset stomach. [1] Some antacids have been used in the treatment of constipation and diarrhea. [2]
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If it is caused by esophagitis, in turn caused by an underlying infection, it is commonly treated by treating the infection (typically with antibiotics). In order to open the stricture, a surgeon can insert a bougie – a weighted tube used to dilate the constricted areas in the esophagus. [3] It can sometimes be treated with other medications.
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