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Fluorouracil (5-FU, 5-fluorouracil), sold under the brand name Adrucil among others, is a cytotoxic chemotherapy medication used to treat cancer. [3] By intravenous injection it is used for treatment of colorectal cancer , oesophageal cancer , stomach cancer , pancreatic cancer , breast cancer , and cervical cancer . [ 3 ]
Acral erythema is a common adverse reaction to cytotoxic chemotherapy drugs, particularly cabozantinib, cytarabine, doxorubicin, and fluorouracil and its prodrug capecitabine. [3] Targeted cancer therapies, especially the tyrosine kinase inhibitors sorafenib and sunitinib, have also been associated with a high incidence of acral erythema ...
Topical 5-fluorouracil (5-FU, Efudex, Carac) has been shown to be an effective therapy for diffuse, but minor actinic cheilitis. 5-fluorouracil works by blocking DNA synthesis. Cells that are rapidly growing need more DNA, so they accumulate more 5-fluorouracil, resulting in their death. Normal skin is much less affected.
Fluorouracil cream, a chemotherapy agent sometimes used to treat skin cancer, can be used on particularly resistant warts, by blocking viral DNA and RNA production and repair. [4] Bleomycin, a more potent chemotherapy drug, can be injected into deep warts, destroying the viral DNA or RNA. Bleomycin is notably not US FDA approved for this purpose.
If the erythema ab igne lesions demonstrate pre-cancerous changes, the use of 5-fluorouracil cream has been recommended. [medical citation needed] Abnormally pigmented skin may persist for years. Treatment with topical tretinoin or laser treatment may improve the appearance. [medical citation needed]
But don’t fret if you splurge on that mac and cheese or ice cream cone once in a while, Passerrello says. “Look at eating patterns over the course of a week, rather than day-to-day.”
The most popular TODAY show recipes in 2024 include Jennifer Garner's blackberry crumble, Donna Kelce's marshmallow dinner rolls and more.
High Fiber Foods. You should rethink eating foods like beans and broccoli until you reach your destination. While good for your body in general, fiber can cause gas and bloating. Digestion of high ...