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As a cream it is used for actinic keratosis, basal cell carcinoma, and skin warts. [4] [5] Side effects of use by injection are common. [3] They may include inflammation of the mouth, loss of appetite, low blood cell counts, hair loss, and inflammation of the skin. [3] When used as a cream, irritation at the site of application usually occurs. [4]
While topical 5-FU is a widely used and cost-effective treatment for AKs and is generally well tolerated, its potential side-effects can include: pain, crusting, redness, and local swelling. [55] These adverse effects can be mitigated or minimized by reducing the frequency of application or taking breaks between uses. [ 55 ]
Acral erythema is a common adverse reaction to cytotoxic chemotherapy drugs, particularly cabozantinib, cytarabine, doxorubicin, and fluorouracil and its prodrug capecitabine. [ 3 ] Targeted cancer therapies , especially the tyrosine kinase inhibitors sorafenib and sunitinib , have also been associated with a high incidence of acral erythema.
Possible side effects include necrosis of the digits, nail loss, and Raynaud syndrome. The usual treatment is one or two injections. [18] [19] Immunotherapy, as intralesional injection of antigens (mumps, candida or trichophytin antigens USP), is a wart treatment that may trigger a host immune response to the wart virus, resulting in wart ...
Medication section, specifically under Fluorouracil Cream: I propose adding the following sentence to the section on medication, specifically in the subheading pertaining to topical Fluorouracil (5-FU) cream: "While topical 5-FU is a widely used and low-cost treatment for AKs, it can cause substantial side-effects, specifically: soreness ...
A 5% 5-fluorouracil (5-FU) cream was used, but it is no longer considered an acceptable treatment due to the side-effects. [28] Podophyllin, podofilox and isotretinoin should not be used during pregnancy, as they could cause birth defects in the fetus.
In people with psoriasis using topical steroids it occurs in up to 5% of people after a year of use. [5] Intermittent use of topical steroids for atopic dermatitis is safe and does not cause skin thinning. [6] [7] [8] Skin atrophy can occur with both prescription and over the counter steroids creams. [9]
Arsenical keratosis (AK) is growth of keratin on the skin caused by arsenic, [1]: 725 which occurs naturally in the Earth's crust and is widely distributed in the environment, [2] Arsenical compounds are used in industrial, agricultural, and medicinal substances.