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The triptan drug class includes 1st generation sumatriptan (which has poor bioavailability), and second generation zolmitriptan. [2] Due to their safety, efficacy and selectivity, triptans are considered first line agents for abortion of migraines. [2]
Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
The effectiveness of new migraine treatments has been compared to paracetamol in a new study, which suggests drugs developed in the 1990s should be more widely promoted to patients with the ...
In 2018, the first medication of a new class of drugs specifically designed for migraine prevention called calcitonin gene-related peptide receptor antagonists (CGRPs) was approved by the FDA. [20] As of July 2023, the FDA has approved eight drugs that act on the CGRP system for use in the treatment of migraine. [21]
Zavzpret is a new nasal spray to treat migraine headaches in adults. But how does the medication work and who should try the new FDA-approved medication?
Triptans are a family of tryptamine-based drugs used as abortive medication in the treatment of migraines and cluster headaches. They are selective 5-hydroxytryptamine/serotonin 1B/1D (5-HT 1B/1D) agonists. [1] Migraine is a complex disease which affects about 15% of the population and can be highly disabling. [2]
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