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H1299, also known as NCI-H1299 [1] [2] or CRL-5803, [3] is a human non-small cell lung carcinoma cell line derived from the lymph node, which is widely used in research. [4]As with other immortalized cell lines, H1299 cells can divide indefinitely.
This list, containing 488 cell lines, was last updated on 1 December 2016. [c] Cellosaurus also is maintaining a list of "problematic" cell lines. [6] The list is dynamically generated from all cell lines in the database with a comment containing the dedicated words "Problematic cell line". As of 17 January 2017, the list contains 757 entries.
NCI/ADR-RES appears to have been derived at some point in time from cell line OVCAR-8. [8] Originally the cell line was named MCF-7/ADR-RES; it was renamed together with the change in classification. [8] Two brain cancer cell lines, SNB-19 and U251, were discovered to come from the same person. [9] This makes a mixup likely.
A cell strain is derived either from a primary culture or a cell line by the selection or cloning of cells having specific properties or characteristics which must be defined. Cell strains are cells that have been adapted to culture but, unlike cell lines, have a finite division potential.
This page was last edited on 23 November 2019, at 17:55 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
The story of how the HeLa cell line came to be was also the subject of a 2010 episode of the podcast Radiolab. [69] HeLa cells were the subject of a 2010 book by Rebecca Skloot, The Immortal Life of Henrietta Lacks, investigating the historical context of the cell line and how the Lacks family was involved in its use. [14]
It need not snow Dec. 25 to fit the weather service's definition of a white Christmas: There just needs to be at least 1 inch of snow on the ground. A trace amount of snow does not count.
Isogenic cell lines are created via a process called homologous gene-targeting. Targeting vectors that utilize homologous recombination are the tools or techniques that are used to knock-in or knock-out the desired disease-causing mutation or SNP (single nucleotide polymorphism) to be studied.