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A549 has also been employed in viral research and associated protein expression changes as a consequence of viral infection. [10] Although A549 is a cancer cell line, it has also been studied for its response to tuberculosis, specifically the production of chemokines as it is induced by the invading bacteria. [11]
[69] 4) Butyric acid inhibited the proliferation of and triggered apoptosis in cultured human A549 lung cancer cells; [70] further studies in A549 as well as H1299 human lung cancer cells found that propionic acid inhibited their stimulated migration, invasiveness, and colony growth in cell culture assays but did not do so in FFAR2 gene ...
A549 cells – derived from a cancer patient lung tumor; HeLa cells – a widely used human cell line isolated from cervical cancer patient Henrietta Lacks; HEK 293 cells – derived from human fetal cells; Huh7 cells – hepatocyte-derived carcinoma cell line; Jurkat cells – a human T lymphocyte cell line isolated from a case of leukemia
H1299, also known as NCI-H1299 [1] [2] or CRL-5803, [3] is a human non-small cell lung carcinoma cell line derived from the lymph node, which is widely used in research. [ 4 ] As with other immortalized cell lines, H1299 cells can divide indefinitely.
K562 cells were the first human immortalised myelogenous leukemia cell line to be established. K562 cells are of the erythroleukemia type, and the cell line is derived from a 53-year-old female chronic myelogenous leukemia patient in blast crisis.
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Salicylaldehyde pyrazole hydrazone (SPH) derivatives were found to inhibit the growth of A549 lung carcinoma cells. [146] SPH has identical ligands for Cu 2+ as SBH. The Cu-SPH complex was found to induce apoptosis in A549, H322 and H1299 lung cancer cells. [147]