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The Fugates, commonly known as the "Blue Fugates" [1] or the "Blue People of Kentucky", are an ancestral family living in the hills of Kentucky starting in the 19th century, where they are known for having a genetic trait that led to the blood disorder methemoglobinemia, causing the skin to appear blue.
Inbreeding is also used to reveal deleterious recessive alleles, which can then be eliminated through assortative breeding or through culling. In plant breeding, inbred lines are used as stocks for the creation of hybrid lines to make use of the effects of heterosis. Inbreeding in plants also occurs naturally in the form of self-pollination.
People's Helpers is an Amish-organized network of mental health caregivers who help families dealing with mental illness and recommend professional counselors. [18] Suicide rates for the Amish of Lancaster County were 5.5 per 100,000 in 1980, about half that of the general population. [a]
In both humans and animals, it can be the result of inbreeding. [10] Unlike alveolar or maxillary prognathism, which are common traits in some populations, mandibular prognathism is typically pathological. However, it is more common among East Asian populations but overall, the condition is polygenic. [11]
It occurs in humans and certain breeds of domesticated animals. Heterochromia of the eye is called heterochromia iridum or heterochromia iridis. It can be complete, sectoral, or central. In complete heterochromia, one iris is a different color from the other. In sectoral heterochromia, part of one iris is a different color from its remainder.
In 1909, Frank Crazier Knowles published a study in the Journal of the American Medical Association describing how he had deliberately infected two children in an orphanage with Molluscum contagiosum—a virus that causes wart-like growths but usually disappears entirely—after an outbreak in the orphanage, to study the disease. The author ...
The following is a list of genetic disorders and if known, type of mutation and for the chromosome involved. Although the parlance "disease-causing gene" is common, it is the occurrence of an abnormality in the parents that causes the impairment to develop within the child. There are over 6,000 known genetic disorders in humans.
On the other hand, there is also evidence for positive selection for albinism in some animals, [33] as well as cultural selection favoring albino people in some human societies, which results in the increase of genes associated with albinism. [34] The founder effect may explain why some animal populations become selected for albinism. [35]