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Electrochemical aptamer-based (E-AB) biosensors is a device that takes advantage of the electrochemical and biological properties of aptamers to take real time, in vivo measurements. An electrochemical aptamer-based (E-AB) biosensor generates an electrochemical signal in response to specific target binding in vivo [ 3 ] The signal is measured ...
A notable recent application involves using laser-induced self-N-doped porous graphene in miRNA biosensors, capable of detecting miRNA hsa-miR-486-5p at concentrations as low as 10 fM. This approach combines cost-effectiveness with high reproducibility, offering significant advantages for conditions like preeclampsia.
[77] [78] Development of wearable biosensors is among such studies. [79] The elimination of lab testing can save time and money. An application of a POCT biosensor can be for the testing of HIV in areas where it is difficult for patients to be tested. A biosensor can be sent directly to the location and a quick and easy test can be used.
Another cancer related application, though still in mice probing stage, is the use of peptide-coated nanoparticles as activity-based sensors to detect lung cancer. The two main advantages of the use of nanoparticles to detect diseases is that it allows early stage detection, as it can detect tumors the size in the order of millimeters.
Joseph Wang (born in 1948) is an American biomedical engineer and inventor. He is a Distinguished Professor, SAIC Endowed Chair, and former Chair of the Department of Nanoengineering at the University of California, San Diego, who specialized in nanomachines, biosensors, nano-bioelectronics, wearable devices, and electrochemistry.
Biosensor used NLR (neutrophil-to-lymphocyte ratio) Elevates with inflammation caused by cancer [75] No Basic Fibroblast Growth Factor (bFGF) This level increases when a tumor is present, helps with the fast reproduction of tumor cells [76] Electrochemical [77] Insulin-like Growth Factor (IGF-R) High activity in cancer cells, help reproduction [78]
Therefore, sialyl Lewis x is being used as a target in studies to fight tumors and cancer cell growth. There is frequent overexpression of sialyl-Lewis X on cancer cells, and it is found on both N-glycan and O-glycans. Sialyl-Lewis X is being researched with CD markers to find new ways to create biosensors for cancer cells. It is also being ...
Wei Gao is a Chinese-American biomedical engineer who currently serves as a professor of medical engineering at the California Institute of Technology (Caltech). [1] Gao has been a professor at Caltech since 2017 and is an associate editor of the journals Science Advances, Biosensors and Bioelectronics, npj Flexible Electronics (), Journal on Flexible Electronics (), and Sensors & Diagnosis ...
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