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Mammalian cochlear hair cells are of two anatomically and functionally distinct types, known as outer, and inner hair cells. Damage to these hair cells results in decreased hearing sensitivity, and because the inner ear hair cells cannot regenerate, this damage is permanent. [4]
The basic structure and function of the fish's inner ear is similar to that of other vertebrates. Mammals share homologous genes with zebrafish that are known to affect inner ear structure and function. [17] In zebrafish, spontaneous and damage-induced hair cell regeneration has been demonstrated in the inner ear.
Abnormal structure/organization of a bundle of stereocilia can also cause deafness and in turn create balance problems for an individual. In other vertebrates, if the hair cell is harmed, supporting cells will divide and replace the damaged hair cells. [2]
Outer hair cells (OHCs) contribute to the structure of the Organ of Corti, which is situated between the basilar membrane and the tectorial membrane within the cochlea (See Figure 3). The tunnel of corti, which runs through the Organ of Corti, divides the OHCs and the inner hair cells (IHCs).
This is called noise-induced hearing loss (NIHL), and it happens when the tiny hair cells in your inner ear are damaged. These hair cells cannot grow back or be repaired, so once they are gone ...
The organ of Corti is located in the scala media of the cochlea of the inner ear between the vestibular duct and the tympanic duct and is composed of mechanosensory cells, known as hair cells. [2] Strategically positioned on the basilar membrane of the organ of Corti are three rows of outer hair cells (OHCs) and one row of inner hair cells ...
Stereocilia (or stereovilli or villi) are non-motile apical cell modifications.They are distinct from cilia and microvilli, but are closely related to microvilli.They form single "finger-like" projections that may be branched, with normal cell membrane characteristics.
The hair cells are the primary auditory receptor cells and they are also known as auditory sensory cells, acoustic hair cells, auditory cells or cells of Corti. The organ of Corti is lined with a single row of inner hair cells and three rows of outer hair cells. The hair cells have a hair bundle at the apical surface of the cell.