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Losartan/hydrochlorothiazide, sold under the brand name Hyzaar among others, is a fixed-dose combination medication used to treat high blood pressure when losartan is not sufficient. [ 1 ] [ 2 ] It consists of losartan, an angiotensin II receptor blocker ; and hydrochlorothiazide , a thiazide diuretic .
Losartan is excreted in the urine, and in the feces via bile, as unchanged drug and metabolites. [47] About 4% of an oral dose is excreted unchanged in urine, and about 6% is excreted in urine as the active metabolite. [48] The terminal elimination half-lives of losartan and EXP3174 are about 1.5 to 2.5 hours and 3 to 9 hours, respectively. [49]
Losartan, the first ARB. Angiotensin II receptor blockers (ARBs), formally angiotensin II receptor type 1 (AT 1) antagonists, [1] also known as angiotensin receptor blockers, [2] [3] angiotensin II receptor antagonists, or AT 1 receptor antagonists, are a group of pharmaceuticals that bind to and inhibit the angiotensin II receptor type 1 (AT 1) and thereby block the arteriolar contraction and ...
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The company announced a "potential" new price of $178. Consumer electronics retailer Best Buy CEO Corie Barry similarly said on its latest earnings call that the goods it sells could become more ...
Prescription drug list prices in the United States continually are among the highest in the world. [1] [2] The high cost of prescription drugs became a major topic of discussion in the 21st century, leading up to the American health care reform debate of 2009, and received renewed attention in 2015.
Enalapril/hydrochlorothiazide (trade name Enalapril comp), wherein enalapril is the ACE inhibitor and hydrochlorothiazide is the thiazide. Quinapril /hydrochlorothiazide (trade name Accuretic) [ 2 ] Lisinopril/hydrochlorothiazide is marketed as Prinzide, [ 3 ] Zestoretic, [ 4 ] and many others.
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