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2. Stem cell transplantation for articular cartilage repair

   en.wikipedia.org/wiki/Stem_cell_transplantation...

   Stem cells, as a concept, originated as a theory in the 19th century to potentially allow certain tissues to self-renew. There are five types of stem cells, and MSC's are multi-potent, meaning they are cells that have the ability to develop into more than one type of specialized cell. Mesenchymal stem cells were originally discovered and ...

3. Knee cartilage replacement therapy - Wikipedia

   en.wikipedia.org/wiki/Knee_cartilage_replacement...

   Because mesenchymal stem cells may regenerate cartilage, cartilage growth in human knees using autologous cultured mesenchymal stem cells is under research and preliminary clinical use, and appears to be safe as of 2016. [11] An advantage to this approach is that a person's own stem cells are used, avoiding tissue rejection by the immune system ...

4. Articular cartilage repair - Wikipedia

   en.wikipedia.org/wiki/Articular_cartilage_repair

   In particular, mesenchymal stem cells have been shown in animal models to regenerate cartilage. Recently, there has been a published case report of decrease in knee pain in a single individual using autologous mesenchymal stem cells. An advantage to this approach is that a person's own stem cells are used, avoiding transmission of genetic diseases.

5. Autologous chondrocyte implantation - Wikipedia

   en.wikipedia.org/wiki/Autologous_Chondrocyte...

   Techniques such as the EELS-TALC [4] to enhance ACI and its next generation advancement called Matrix Assisted Chondrocyte Implantation (MACI) [5] with enabling chondrocytes to be tissue engineered with long term native knee cartilage phenotype maintenance in vitro and in vivo, [6] [7] with the engineered tissue construct containing stem cell progenitors [8] along with those expressing ...

6. Articular cartilage stem cell paste grafting - Wikipedia

   en.wikipedia.org/wiki/Articular_cartilage_stem...

   Articular cartilage stem cell paste grafting was initially described by Kevin R. Stone M.D., a San Francisco-based orthopedic surgeon, in 1997 . The technique was devised in response to reports that many of the contemporary cartilage restoration procedures lead to the development of fibrocartilage , not true hyaline articular cartilage .

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