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  2. Metastatic breast cancer - Wikipedia

    en.wikipedia.org/wiki/Metastatic_breast_cancer

    Metastatic breast cancer to the lung or pleura causes chronic cough, dyspnea, abnormal chest X-ray, and chest pain. Other nonspecific systemic symptoms of metastatic breast cancer include fatigue, malaise, weight loss, and poor appetite. Sometimes people with metastatic breast cancer do not have any notable changes or symptoms. [8]

  3. Breast cancer - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer

    This is an accepted version of this page This is the latest accepted revision, reviewed on 3 March 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on the ...

  4. Metastasis - Wikipedia

    en.wikipedia.org/wiki/Metastasis

    The tumor in the lung is then called metastatic breast cancer, not lung cancer. Metastasis is a key element in cancer staging systems such as the TNM staging system, where it represents the "M". In overall stage grouping, metastasis places a cancer in Stage IV. The possibilities of curative treatment are greatly reduced, or often entirely ...

  5. Tumour heterogeneity - Wikipedia

    en.wikipedia.org/wiki/Tumour_heterogeneity

    Evidence of the cancer stem cell model has been demonstrated in multiple tumour types including leukemias, [21] [22] glioblastoma, [23] breast cancer, [24] and prostate cancer. [25] However, the existence of CSCs is still under debate. One reason for this is that markers for CSCs have been difficult to reproduce across multiple tumours.

  6. Cancer - Wikipedia

    en.wikipedia.org/wiki/Cancer

    The most common as of 2018 are lung cancer (1.76 million deaths), colorectal cancer (860,000) stomach cancer (780,000), liver cancer (780,000), and breast cancer (620,000). [2] This makes invasive cancer the leading cause of death in the developed world and the second leading in the developing world . [ 25 ]

  7. Malignant transformation - Wikipedia

    en.wikipedia.org/wiki/Malignant_transformation

    Colon cancer provides one example of the mechanisms by which diet, the top factor listed in the table, is an external factor in cancer. The Western diet of African Americans in the United States is associated with a yearly colon cancer rate of 65 per 100,000 individuals, while the high fiber/low fat diet of rural Native Africans in South Africa is associated with a yearly colon cancer rate of ...

  8. Progression-free survival - Wikipedia

    en.wikipedia.org/wiki/Progression-free_survival

    Progression-free survival (PFS) is "the length of time during and after the treatment of a disease, such as cancer, that a patient lives with the disease but it does not get worse". [1] In oncology, PFS usually refers to situations in which a tumor is present, as demonstrated by laboratory testing, radiologic testing, or clinically. Similarly ...

  9. Breast cancer stem cell - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer_stem_cell

    The most commonly used treatment methods for breast cancer include surgery, radiotherapy and chemotherapy. [2] Some of these treated patients experience disease relapse and metastasis. The aggressive progression and recurrence of this disease has been attributed the presence of a subset of tumor cells known as breast cancer stem cells (BCSCs).

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