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The toxic effects of ingesting ethylene glycol occur because it is converted by the liver into 4 other chemicals that are much more toxic. The lethal dose of pure ethylene glycol is 1.4 ml/kg (3 US fluid ounces (90 ml) is lethal to a 140-pound (64 kg) person) but is much less lethal if treated within an hour. [9] (see Ethylene glycol poisoning).
Patricia Stallings (born 1964 or 1965) is an American woman who was wrongfully convicted of murder after the death of her son Ryan on September 7, 1989. Because testing seemed to indicate an elevated level of ethylene glycol in Ryan's blood, authorities suspected antifreeze poisoning and they arrested Stallings the next day.
Antifreeze products for automotive use containing propylene glycol in place of ethylene glycol are available, and are generally considered safer to use, as it possesses an unpleasant taste in contrast to the perceived "sweet" taste of toxic ethylene glycol-based coolants, and produces only lactic acid in an animal's body, as their muscles do ...
Unlike the widely used automotive antifreeze, ethylene glycol, AFPs do not lower freezing point in proportion to concentration. [citation needed] Rather, they work in a noncolligative manner. This phenomenon allows them to act as an antifreeze at concentrations 1/300th to 1/500th of those of other dissolved solutes.
Family matriarch Diane Staudte and her daughter, Rachel Staudte, committed the crimes together using antifreeze purchased off the internet, with the rationale that antifreeze sold online would not contain the added bittering agent in commercial chemicals making the ethylene glycol poison detectable.
Conventional cryoprotectants are glycols (alcohols containing at least two hydroxyl groups), such as ethylene glycol [citation needed], propylene glycol and glycerol. Ethylene glycol is commonly used as automobile antifreeze; while propylene glycol has been used to reduce ice formation in ice cream.
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