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Nontreponemal tests are an indirect method in that they detect biomarkers that are released during cellular damage that occurs from the syphilis spirochete. In contrast, treponemal tests look for antibodies that are a direct result of the infection thus, anti-treponeme IgG, IgM and to a lesser degree IgA.
The rapid plasma reagin test (RPR test or RPR titer) is a type of rapid diagnostic test that looks for non-specific antibodies in the blood of the patient that may indicate an infection by syphilis or related non-venereal treponematoses. It is one of several nontreponemal tests for syphilis (along with the Wassermann test and the VDRL test).
In tertiary syphilis, there are gummas (soft, non-cancerous growths), neurological problems, or heart symptoms. [3] Syphilis has been known as "the great imitator", because it may cause symptoms similar to many other diseases. [2] [3] Primary syphilis on the tounge. Syphilis is most commonly spread through sexual activity. [2]
The Venereal Disease Research Laboratory test (VDRL) is a blood test for syphilis and related non-venereal treponematoses that was developed by the eponymous US laboratory. . The VDRL test is used to screen for syphilis (it has high sensitivity), whereas other, more specific tests are used to diagnose the disea
A new proven protocol in which doxycycline is used to prevent sexually transmitted infections — called doxyPEP — has been an apparent sleeper hit among gay and bisexual men.
The fluorescent treponemal antibody absorption (FTA-ABS) test is a diagnostic test for syphilis.Using antibodies specific for the Treponema pallidum species, such tests would be assumed to be more specific than non-treponemal testing such as VDRL but have been shown repeatedly to be sensitive but not specific for the diagnosis of neurosyphilis in cerebrospinal fluid (CSF).
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Syphilis has four distinct stages, and each has its own symptoms. The CDC breaks it down this way: Primary stage. During this stage, someone may notice a single sore or multiple sores, and it's ...
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