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  2. URA3 - Wikipedia

    en.wikipedia.org/wiki/URA3

    URA3 is often used in yeast research as a "marker gene", that is, a gene to label chromosomes or plasmids. URA3 encodes Orotidine 5'-phosphate decarboxylase (ODCase) , which is an enzyme that catalyzes one reaction in the synthesis of pyrimidine ribonucleotides (a component of RNA ).

  3. Yeast deletion project - Wikipedia

    en.wikipedia.org/wiki/Yeast_deletion_project

    The yeast deletion project, formally the Saccharomyces Genome Deletion Project, is a project to create data for a near-complete collection of gene-deletion mutants of the yeast Saccharomyces cerevisiae. Each strain carries a precise deletion of one of the genes in the genome. This allows researchers to determine what each gene does by comparing ...

  4. 5-Fluoroorotic acid - Wikipedia

    en.wikipedia.org/wiki/5-Fluoroorotic_Acid

    5-Fluoroorotic acid (5FOA) is a fluorinated derivative of the pyrimidine precursor orotic acid.It is used in yeast genetics to select for the absence of the URA3 gene, which encodes the enzyme for the decarboxylation of 5-fluoroorotic acid to 5-fluorouracil, a toxic metabolite. [1]

  5. Synthetic genetic array - Wikipedia

    en.wikipedia.org/wiki/Synthetic_genetic_array

    Synthetic genetic array analysis is generally conducted using colony arrays on petriplates at standard densities (96, 384, 768, 1536). To perform a SGA analysis in S.cerevisiae, the query gene deletion is crossed systematically with a deletion mutant array (DMA) containing every viable knockout ORF of the yeast genome (currently 4786 strains). [9]

  6. Selectable marker - Wikipedia

    en.wikipedia.org/wiki/Selectable_marker

    A selectable marker is a gene introduced into cells, especially bacteria or cells in culture, which confers one or more traits suitable for artificial selection.They are a type of reporter gene used in laboratory microbiology, molecular biology, and genetic engineering to indicate the success of a transfection or transformation or other procedure meant to introduce foreign DNA into a cell.

  7. Michigan Court declines to hear appeal of ex-officer charged ...

    www.aol.com/michigan-court-declines-hear-appeal...

    The Michigan Supreme Court declined to hear an appeal Monday from a former police officer who is charged with killing a 26-year-old Black man during a traffic stop.. Christopher Schurr was fired ...

  8. Donald Trump praises Elon Musk after ringing bell at New York ...

    www.aol.com/news/donald-trump-praises-elon-musk...

    NEW YORK, NEW YORK - DECEMBER 12: President-elect Donald Trump rings the opening bell on the trading floor of the New York Stock Exchange (NYSE) on December 12, 2024 in New York City.

  9. Mehmet Oz's controversial health claims, from the HCG ... - AOL

    www.aol.com/news/mehmet-ozs-controversial-health...

    In a BMJ study from 2014, for instance, researchers evaluated health claims made on 40 randomly selected episodes of “The Dr. Oz Show,” a syndicated daytime TV show that ran from 2009 to 2022 ...