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2. Alleviates Hunger. Metformin improves how well your cells respond to insulin. This helps regulate your blood sugar levels and manage spikes in insulin that can trigger hunger and food cravings.
While it was once “just” a medication for people with type 2 diabetes, metformin is now thought of as a “wonder drug with multiple potentials,” says David Cutler, M.D., a family medicine ...
A smaller study on metformin also found that the average weight lost in 154 patients was between 5.6 and 7 kilograms — or 13 to 15 pounds. ... and a review of your personal medical history.
A Cochrane review, though, found that metformin was only slightly effective for decreasing androgen levels in women with PCOS. [124] Metformin also has significant effects on the gut microbiome, such as its effect on increasing agmatine production by gut bacteria, but the relative importance of this mechanism compared to other mechanisms is ...
i think the relative importance of using metformin in the treatment of type 2 diabetes mellitus should be underlined given the results of the united kingdom prospective diabetes study (ukpds). it was the only agent that reduced cardiovascular mortality and morbidity - if i had type 2, i'd be the first in line to want metformin, ahead of sulphonylureas etc.
In the United States, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. [5] [6]In the European Union, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in people with type 2 diabetes; in combination with a sulfonylurea as an adjunct to diet and exercise "in people ...
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