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Botulism is a rare and potentially fatal illness caused by botulinum toxin, which is produced by the bacterium Clostridium botulinum. The disease begins with weakness, blurred vision, feeling tired , and trouble speaking.
Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species. [24] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction , thus causing flaccid paralysis . [ 25 ]
Along with some strains of Clostridium butyricum and Clostridium baratii, these bacteria all produce the toxin. [2] Botulinum toxin can cause botulism, a severe flaccid paralytic disease in humans and other animals, [3] and is the most potent toxin known to science, natural or synthetic, with a lethal dose of 1.3–2.1 ng/kg in humans. [4] [5]
Common examples of neurotoxins include lead, [7] ethanol (drinking alcohol), [8] glutamate, [9] nitric oxide, [10] botulinum toxin (e.g. Botox), [11] tetanus toxin, [12] and tetrodotoxin. [6] Some substances such as nitric oxide and glutamate are in fact essential for proper function of the body and only exert neurotoxic effects at excessive ...
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Histone modification does not involve the pore-forming activity of the CDCs. RTX toxins; RTX toxins can be identified by the presence of a specific tandemly repeated nine-amino acid residue sequence in the protein. The prototype member of the RTX toxin family is haemolysin A (HlyA) of E. coli. [citation needed] RTX is also found in Legionella ...
Pasta is often one of the first foods many people avoid when attempting to lose weight or change their body composition. However, pasta and grains in general (specifically whole grains) can be an ...
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