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  2. Sexual differentiation in humans - Wikipedia

    en.wikipedia.org/wiki/Sexual_differentiation_in...

    Sexual differentiation includes development of different genitalia and the internal genital tracts and body hair plays a role in sex identification. [ 2 ] The development of sexual differences begins with the XY sex-determination system that is present in humans, and complex mechanisms are responsible for the development of the phenotypic ...

  3. Sex differences in humans - Wikipedia

    en.wikipedia.org/wiki/Sex_differences_in_humans

    [16] [17] IQ tests that measure fluid g and have not been constructed to eliminate sex differences also tend to show that sex differences are either non-existent or negligible. [17] [18] 2008 research found that, for grades 2 to 11, there were no significant gender differences in math skills among the general population. [19]

  4. XY sex-determination system - Wikipedia

    en.wikipedia.org/wiki/XY_sex-determination_system

    All animals have a set of DNA coding for genes present on chromosomes. In humans, most mammals, and some other species, two of the chromosomes, called the X chromosome and Y chromosome, code for sex. In these species, one or more genes are present on their Y chromosome that determine maleness.

  5. Sex differences in human physiology - Wikipedia

    en.wikipedia.org/wiki/Sex_differences_in_human...

    The gender gap in life expectancy suggests differences in the aging process between males and females. A key factor underlying aging is considered to be DNA damage, particularly DNA double-strand breaks, and the capability to repair these damages declines with age. [128]

  6. Mutagenesis (molecular biology technique) - Wikipedia

    en.wikipedia.org/wiki/Mutagenesis_(molecular...

    Types of mutations that can be introduced by random, site-directed, combinatorial, or insertional mutagenesis. In molecular biology, mutagenesis is an important laboratory technique whereby DNA mutations are deliberately engineered to produce libraries of mutant genes, proteins, strains of bacteria, or other genetically modified organisms. The ...

  7. Mutagenesis - Wikipedia

    en.wikipedia.org/wiki/Mutagenesis

    DNA may be modified, either naturally or artificially, by a number of physical, chemical and biological agents, resulting in mutations. Hermann Muller found that "high temperatures" have the ability to mutate genes in the early 1920s, [2] and in 1927, demonstrated a causal link to mutation upon experimenting with an x-ray machine, noting phylogenetic changes when irradiating fruit flies with ...

  8. Disorders of sex development - Wikipedia

    en.wikipedia.org/wiki/Disorders_of_sex_development

    Specifically the DSD exists as replacement for the "optimum gender rearing model," which was the standard model for individuals with atypical sexual development. This model stated goal was to assign a gender binary, usually female via non-consensual medicalization, often via the falsification of medical records.

  9. Sex-determining region Y protein - Wikipedia

    en.wikipedia.org/wiki/Sex-determining_region_y...

    In humans, the SRY gene is located on short (p) arm of the Y chromosome at position 11.2. Sex-determining region Y protein (SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein/transcription factor) encoded by the SRY gene that is responsible for the initiation of male sex determination in therian mammals (placentals and marsupials). [5]