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  2. Oxycodone - Wikipedia

    en.wikipedia.org/wiki/Oxycodone

    Oxycodone is used for managing moderate to severe acute or chronic pain when other treatments are not sufficient. [15] It may improve quality of life in certain types of pain. [25] Numerous studies have been completed, and the appropriate use of this compound does improve the quality of life of patients with long term chronic pain syndromes ...

  3. Opioid - Wikipedia

    en.wikipedia.org/wiki/Opioid

    In older adults, opioid use is associated with increased adverse effects such as "sedation, nausea, vomiting, constipation, urinary retention, and falls". [72] As a result, older adults taking opioids are at greater risk for injury. [73] Opioids do not cause any specific organ toxicity, unlike many other drugs, such as aspirin and

  4. Oxycodone/naloxone - Wikipedia

    en.wikipedia.org/wiki/Oxycodone/naloxone

    A 2008 study demonstrated a significant reduction in constipation. [6] Oxycodone/naloxone was released in 2014 in the United States, [5] in 2006 in Germany, and has been available in some other European countries since 2009. In the United Kingdom, the 10 mg oxycodone / 5 mg naloxone and 20 mg / 10 mg strengths were approved in December 2008 ...

  5. μ-opioid receptor - Wikipedia

    en.wikipedia.org/wiki/Μ-opioid_receptor

    Activation of the μ-opioid receptor by an agonist such as morphine causes analgesia, sedation, slightly reduced blood pressure, itching, nausea, euphoria, decreased respiration, miosis (constricted pupils), and decreased bowel motility often leading to constipation. Some of these effects, such as analgesia, sedation, euphoria, itching and ...

  6. Opioid withdrawal - Wikipedia

    en.wikipedia.org/wiki/Opioid_withdrawal

    The withdrawal from various opioid medications, including morphine, causes similar effects, most of which is caused by stimulation and over-stimulation of the central nervous system. [ 9 ] [ 7 ] The effects of morphine withdrawal can range from gastrointestinal disturbances to symptoms like tremors (involuntary shaking, most commonly in hands ...

  7. Why norovirus is so hard to kill: Here's how to protect ... - AOL

    www.aol.com/why-norovirus-hard-kill-heres...

    There’s currently no approved vaccine for norovirus, although Moderna has begun a phase three trial in the U.S. for a vaccine using mRNA technology and aims to test it in 25,000 adults worldwide.

  8. Constipation - Wikipedia

    en.wikipedia.org/wiki/Constipation

    Constipation is a bowel dysfunction that makes bowel movements infrequent or hard to pass. [2] The stool is often hard and dry. [4] Other symptoms may include abdominal pain, bloating, and feeling as if one has not completely passed the bowel movement. [3]

  9. How much is too much alcohol over the holidays? A doctor explains

    www.aol.com/much-too-much-alcohol-over-122302553...

    CNN: Why is too much alcohol considered a health hazard? Dr. Leana Wen: There is abundant research showing that excessive drinking on a regular basis is associated with many chronic illnesses ...