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In control systems, sliding mode control (SMC) is a nonlinear control method that alters the dynamics of a nonlinear system by applying a discontinuous control signal (or more rigorously, a set-valued control signal) that forces the system to "slide" along a cross-section of the system's normal behavior.
Variable structure control (VSC) is a form of discontinuous nonlinear control. The method alters the dynamics of a nonlinear system by application of a high-frequency switching control . The state - feedback control law is not a continuous function of time; it switches from one smooth condition to another.
Sheet moulding compound (SMC) or sheet moulding composite is a ready to mould glass-fibre reinforced polyester material primarily used in compression moulding. [1] The sheet is provided in rolls weighing up to 1000 kg. Alternatively the resin and related materials may be mixed on site when a producer wants greater control over the chemistry and ...
The dynamic nature of loop extrusion is tightly controlled by accessory factors and post-translational modifications, especially in the case of cohesin. In vertebrates, NIPBL (and orthologs like Mau2 in yeast or SCC2 and SCC4) is crucial for loading SMC complexes onto DNA, initiating and maintaining active extrusion. PDS5 is thought to pause ...
SMC's head office is located in Sotokanda, Chiyoda-ku, Tokyo, Japan. The company has a global engineering network, with technical facilities in the United States, Europe, and China, as well as Japan. Key production facilities are located in China and Singapore, and local production facilities are in United States, Mexico, Brazil, Europe, India ...
An emerging area of robust control from application point of view is sliding mode control (SMC), which is a variation of variable structure control (VSC). The robustness properties of SMC with respect to matched uncertainty as well as the simplicity in design attracted a variety of applications.
SMC dimers form a V-shaped molecule with two long coiled-coil arms. [19] [20] To make such a unique structure, an SMC protomer is self-folded through anti-parallel coiled-coil interactions, forming a rod-shaped molecule. At one end of the molecule, the N-terminal and C-terminal domains form an ATP-binding domain. The other end is called a hinge ...
The head domains of SMC proteins contain ATPase sites that drive cohesin's dynamic interactions with DNA, mostly loop extrusion. Conformational Flexibility. Cohesin is a highly dynamic protein, which exist in the open and closed conformations, interchanging by bending in the so-called elbows (see Loop extrusion for more). Regulatory Interactions.