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Cholangiocarcinoma, also known as bile duct cancer, is a type of cancer that forms in the bile ducts. [2] ... In Phase III clinical trials, durvalumab, ...
Durvalumab, [8] sold under the brand name Imfinzi, ... Fifty-six percent had intrahepatic cholangiocarcinoma, 25% had gallbladder cancer, and 19% had extrahepatic ...
Infigratinib is currently in clinical trials for the treatment of children with achondroplasia.Infigratinib is now in a Phase 3 clinical trial. [12]Infigratinib was originally developed at a higher dose for the treatment of adults with previously treated, unresectable locally advanced or metastatic cholangiocarcinoma (bile duct cancer) with a fibroblast growth factor receptor 2 (FGFR2) fusion ...
Tremelimumab is indicated, in combination with durvalumab, for the treatment of adults with unresectable hepatocellular carcinoma. [7] [11] [8]Tremelimumab in combination with durvalumab and platinum-based chemotherapy is indicated for the first-line treatment of adults with metastatic non-small cell lung cancer with no sensitizing epidermal growth factor receptor mutations or anaplastic ...
Silmitasertib is in clinical trials for use as an adjunct to chemotherapy in the treatment of cholangiocarcinoma (bile duct cancer), [1] is in phase I and II clinical trials for the treatment of recurrent Sonic Hedgehog (SHH) medulloblastoma, [2] [3] and in preclinical development for other cancers, including hematological and lymphoid ...
Durvalumab [1] AstraZeneca UK: unresectable Stage III non-small cell lung cancer: Ibalizumab-uiyk [1] Theratechnologies: human immunodeficiency virus type 1 (HIV-1) infection Brentuximab vedotin [1] Seattle Genetics: Hodgkin lymphoma: Ipilimumab [1] Bristol-Myers Squibb: renal cell carcinoma: Nivolumab [1] Bristol-Myers Squibb: renal cell ...
Futibatinib, sold under the brand name Lytgobi, is an anti-cancer medication used for the treatment of cholangiocarcinoma (bile duct cancer). [ 1 ] [ 3 ] It is a kinase inhibitor. [ 1 ] [ 6 ] It is taken by mouth .
Pemigatinib, sold under the brand name Pemazyre, is an anti-cancer medication used for the treatment of bile duct cancer (cholangiocarcinoma). [5] [6] [8] [9] Pemigatinib works by blocking FGFR2 in tumor cells to prevent them from growing and spreading. [8] Pemigatinib belongs to a group of medicines called protein kinase inhibitors. [10]