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Most people recover within a week or so. In about 5% of cases, symptoms worsen and can become life-threatening. This is called severe dengue (formerly called dengue hemorrhagic fever or dengue shock syndrome). [21] [23] Severe dengue can lead to shock, internal bleeding, organ failure and even death. [24]
Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
A viral hemorrhagic fever is a possible cause of the Plague of Athens during the Peloponnesian War. [13] A viral hemorrhagic fever is an alternate theory of the cause of the Black Death and the Plague of Justinian [14] The initial, and currently only, outbreak of Lujo virus in September–October 2008 left four of five patients dead. [15]
It is not entirely clear why secondary infection with a different strain of dengue virus places people at risk of dengue hemorrhagic fever and dengue shock syndrome. The most widely accepted hypothesis is that of antibody-dependent enhancement (ADE). The exact mechanism behind ADE is unclear.
Dengue is a viral fever spread through mosquito bites. It’s common in many tropical regions across the globe, but has recently appeared in more temperate climates. Dengue fever, once confined to ...
The most widely known ADE example occurs with dengue virus. [34] Dengue is a single-stranded positive-polarity RNA virus of the family Flaviviridae. It causes disease of varying severity in humans, from dengue fever (DF), which is usually self-limited, to dengue hemorrhagic fever and dengue shock syndrome, either of which may be life ...
Marburg is a rare but “severe hemorrhagic fever that can cause serious illness and death,” the U.S. Centers for Disease Control says, adding that there is no treatment or vaccine for it.
Under the program, authorities release special mosquitoes bred to carry a bacteria called Wolbachia, which blocks the transmission of viruses that cause dengue, zika, and yellow fever. However ...