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Glycolic acid is the major metabolite of ethylene glycol responsible for toxicity. The three main systems affected by ethylene glycol poisoning are the central nervous system, metabolic processes, and the kidneys. [7] The central nervous system is affected early in the course of poisoning as the result of a direct action of ethylene glycol.
It is not effective for a number of poisonings including: strong acids or bases, iron, lithium, arsenic, methanol, ethanol or ethylene glycol. [7] Although activated charcoal is the most commonly used agent for GI decontamination in poisoned patients, medical professionals use discretion when determining whether or not its use is indicated. [7]
Methanol toxicity (also methanol poisoning) is poisoning from methanol, characteristically via ingestion. [1] Symptoms may include an altered/decreased level of consciousness, poor or no coordination, vomiting, abdominal pain, and a specific smell on the breath. [1] [2] Decreased vision may start as early as twelve hours after exposure. [2]
Other conditions that may present similarly include other causes of high anion gap metabolic acidosis such as diabetic ketoacidosis, toxic alcohol ingestion, and starvation ketosis. [2] Toxic alcohol ingestion includes methanol and ethylene glycol poisoning. [6] Pancreatitis, alcoholic hepatitis, and gastritis may also result in similar ...
Ethylene glycol has relatively high mammalian toxicity when ingested, roughly on par with methanol, with an oral LD Lo = 786 mg/kg for humans. [30] The major danger is due to its sweet taste, which can attract children and animals. Upon ingestion, ethylene glycol is oxidized to glycolic acid, which is, in turn, oxidized to oxalic acid, which is ...
2. Eat Smaller, More Frequent Meals. Instead of three main meals, try eating smaller, more frequent meals throughout the day. This can help if nausea is making it hard to feel like eating or if ...
The symptoms of an episode of diabetic ketoacidosis usually evolve over a period of about 24 hours. Predominant symptoms are nausea and vomiting, pronounced thirst, excessive urine production and abdominal pain that may be severe. [13] [14] In severe DKA, breathing becomes rapid and of a deep, gasping character, called "Kussmaul breathing".
Depending on the amount of coffee consumed, the loophole method could lead to excessive caffeine intake and related symptoms, such as rapid heart rate, anxiety, insomnia, and digestive issues ...