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Normal vaginal discharge is composed of cervical mucus, vaginal fluid, shedding vaginal and cervical cells, and bacteria. [1] The majority of the liquid in vaginal discharge is mucus produced by glands of the cervix. [1] [4] The rest is made up of transudate from the vaginal walls and secretions from glands (Skene's and Bartholin's). [4]
It is usually a non-pathological symptom secondary to inflammatory conditions of the vagina or cervix. [5] Leukorrhea can be confirmed by finding >10 WBC per high-power field under a microscope when examining vaginal fluid. [6] Vaginal discharge is normal, and causes of change in discharge include infection, malignancy, and hormonal changes.
Changes in the usual color, texture or odor of your vaginal discharge can be a sign of infection. Normal discharge may have a slight scent, for example, but it typically doesn’t have a strong odor.
“The most common cause of vaginal odor is an imbalance in the normal flora in the vagina,” which causes a fishy odor, irritation, and thin to no vaginal discharge, says Dr. Streicher.
Vaginal wet mount showing slings of pseudohyphae of Candida albicans surrounded by round vaginal epithelial cells, conferring a diagnosis of candidal vulvovaginitis.. A vaginal wet mount (or vaginal smear [1] or wet prep [2]) is a gynecologic test wherein a sample of vaginal discharge is observed by wet mount microscopy by placing the specimen on a glass slide and mixing with a salt solution. [1]
The vagina, a fibromuscular canal extending from its external opening in the vulva to the cervix, is primarily composed of smooth muscle covered by a non-keratinized epithelial lining. This lining, until menopause, remains thick, kept moist by fluid from the vaginal wall and mucus from cervical and vestibular glands. [12]
The Bartholin's glands (named after Caspar Bartholin the Younger; also called Bartholin glands or greater vestibular glands) are two pea-sized compound alveolar glands [2] located slightly posterior and to the left and right of the opening of the vagina. [3] They secrete mucus to lubricate the vagina. [3] They are homologous to bulbourethral ...
Trichomonas vaginalis and G. vaginalis have similar clinical presentations and can cause a frothy gray or yellow-green vaginal discharge, pruritus, and produce a positive "whiff-test". The two can be distinguished using a wet-mount slide, where a swab of the vaginal epithelium is diluted and then placed onto a slide for observation under a ...