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The group concluded that patients satisfying 4 of the 16 criteria listed below including at least one of the 10 Clinical criterium and one of the 6 Immunologic criterion had on their initial evaluation a sensitivity (i.e., probability of a positive test result conditioned on the individual truly being positive) of 82.7% and a specificity (i.e ...
Lupus erythematosus may manifest as systemic disease or in a purely cutaneous form also known as incomplete lupus erythematosus. Lupus has four main types: [citation needed] systemic; discoid; drug-induced; neonatal; Of these, systemic lupus erythematosus (also known as SLE) is the most common and serious form.
Among identical twins, if one is affected there is a 24% chance the other one will also develop the disease. [1] Female sex hormones, sunlight, smoking, vitamin D deficiency, and certain infections are also believed to increase a person's risk. [5] The mechanism involves an immune response by autoantibodies against a person's own tissues. [1]
Drug-induced lupus erythematosus is an autoimmune disorder caused by chronic use of certain drugs. These drugs cause an autoimmune response (the body attacks its own cells) producing symptoms similar to those of systemic lupus erythematosus (SLE).
Undifferentiated connective tissue disease (UCTD) (also known as latent lupus or incomplete lupus [1]) is a disease in which the connective tissues are targeted by the immune system. It is a serological and clinical manifestation of an autoimmune disease .
Kaolin clotting time (KCT) is a sensitive test to detect lupus anticoagulants. [2] There is evidence that suggests it is the most sensitive test for detecting lupus anticoagulants. [3] It can also detect factor VIII inhibitors but is sensitive to unfractionated heparin as well. [4]
The Centers for Disease Control and Prevention estimates that more than 200,000 people in the U.S. have lupus, though the Lupus Foundation of America puts the total much higher: roughly 1.5 ...
The score is an acronym for each of the risk factors measured. Each risk factor scores one point, for a maximum score of 5: Confusion of new onset (defined as an AMTS of 8 or less) Blood Urea nitrogen greater than 7 mmol/L (19 mg/dL) Respiratory rate of 30 breaths per minute or greater