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  2. Hypothalamic–pituitary–thyroid axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    Thyrotropic feedback control on a more detailed and quantitative level. [3] Thyroid homeostasis results from a multi-loop feedback system that is found in virtually all higher vertebrates. Proper function of thyrotropic feedback control is indispensable for growth, differentiation, reproduction and intelligence.

  3. Thyroid-stimulating hormone - Wikipedia

    en.wikipedia.org/wiki/Thyroid-stimulating_hormone

    The concentration of thyroid hormones (T 3 and T 4) in the blood regulates the pituitary release of TSH; when T 3 and T 4 concentrations are low, the production of TSH is increased, and, conversely, when T 3 and T 4 concentrations are high, TSH production is decreased. This is an example of a negative feedback loop. [5]

  4. Hypothalamic–pituitary–gonadal axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    Estrogen forms a negative feedback loop by inhibiting the production of GnRH in the hypothalamus. Inhibin acts to inhibit activin, which is a peripherally produced hormone that positively stimulates GnRH-producing cells. Follistatin, which is also produced in all body tissue, inhibits activin and gives the rest of the body more control over the ...

  5. Thyroid - Wikipedia

    en.wikipedia.org/wiki/Thyroid

    The thyroid, or thyroid gland, is an endocrine gland in vertebrates. In humans, it is a butterfly-shaped gland located in the neck below the Adam's apple. It consists of two connected lobes. The lower two thirds of the lobes are connected by a thin band of tissue called the isthmus (pl.: isthmi).

  6. Endocrine system - Wikipedia

    en.wikipedia.org/wiki/Endocrine_system

    At 20 weeks, the fetus is able to implement feedback mechanisms for the production of thyroid hormones. During fetal development, T 4 is the major thyroid hormone being produced while triiodothyronine (T 3 ) and its inactive derivative, reverse T 3 , are not detected until the third trimester.

  7. Adrenal insufficiency - Wikipedia

    en.wikipedia.org/wiki/Adrenal_insufficiency

    Adrenal insufficiency is a condition in which the adrenal glands do not produce adequate amounts of steroid hormones.The adrenal glands—also referred to as the adrenal cortex—normally secrete glucocorticoids (primarily cortisol), mineralocorticoids (primarily aldosterone), and androgens.

  8. Hypothalamic–pituitary–adrenal axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    Schematic of the HPA axis (CRH, corticotropin-releasing hormone; ACTH, adrenocorticotropic hormone) Hypothalamus, pituitary gland, and adrenal cortex The hypothalamic–pituitary–adrenal axis (HPA axis or HTPA axis) is a complex set of direct influences and feedback interactions among three components: the hypothalamus (a part of the brain located below the thalamus), the pituitary gland (a ...

  9. Triiodothyronine - Wikipedia

    en.wikipedia.org/wiki/Triiodothyronine

    Production of T 3 and its prohormone thyroxine (T 4) is activated by thyroid-stimulating hormone (TSH), which is released from the anterior pituitary gland. This pathway is part of a closed-loop feedback process: Elevated concentrations of T 3, and T 4 in the blood plasma inhibit the production of

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