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1q21.1 duplication syndrome arises from microduplications of the BP3-BP4 region, containing at least seven genes and a minimum duplicated region of ~1.2 Mb of unique DNA sequence. [ 7 ] 1q21.1 duplication syndrome has an autosomal dominant inheritance pattern, where 18–50% of deletions happen de novo and 50–82% are inherited from their parents.
As of June 2022, W3Tech's web server count of all web sites ranked Nginx first with 33.6%. Apache was second at 31.4% and Cloudflare Server third at 21.6%. [14] As of March 2022, Netcraft estimated that Nginx served 22.01% of the million busiest websites with Apache a little ahead at 23.04%.