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Opisthotonus or opisthotonos (from Ancient Greek: ὄπισθεν, romanized: opisthen, lit. 'behind' and τÏŒνος , tonos , 'tension') is a state of severe hyperextension and spasticity in which an individual's head, neck and spinal column enter into a complete "bridging" or "arching" position.
Oculogyric crisis and opisthotonus are also very common. Acute effects of dopamine antagonists also include Parkinsons-like symptoms, manifested by bradykinesia, pin rolling tremor, and rigidity of the body. These movements may fluctuate over hours and temporarily dissipate in response to reassurance, and the individual episodes may last ...
Oclacitinib lacks the side effects that most JAK inhibitors have in humans; instead, side effects are infrequent, mild, and mostly self-limiting. [13] [14] [16] The most common side effects are gastrointestinal problems (vomiting, diarrhea, and appetite loss) and lethargy. The GI problems can sometimes be alleviated by giving oclacitinib with food.
pimobendan – phosphodiesterase 3 inhibitor used to manage heart failure in dogs; pirlimycin – antimicrobial; ponazuril – anticoccidial; praziquantel – treatment of infestations of the tapeworms Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus; prazosin – sympatholytic used in hypertension and abnormal muscle contractions
Signs include vomiting, diarrhea, collapse, difficulty breathing, and body temperature approaching 42 °C to 43 °C. Treatment includes cooling the dogs with wet towels and fans, intravenous fluid therapy, and other supportive care. [171] If a dog's temperature begins to drop to around 40 °C, stop the cooling process.
In dogs with transitional cell carcinomas, surgery is sometimes done when only a single tumor is present in the bladder. Most dogs, however, will need radiation, chemotherapy, and other medications.
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