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Melanin is produced through a multistage chemical process known as melanogenesis, where the oxidation of the amino acid tyrosine is followed by polymerization. Pheomelanin is a cysteinated form containing poly benzothiazine portions that are largely responsible for the red or yellow tint given to some skin or hair colors.
Vitiligo is a skin disease where people lack melanin in certain areas in the skin. People with oculocutaneous albinism typically have a very low level of melanin production. Albinism is often but not always related to the TYR gene coding the tyrosinase enzyme. Tyrosinase is required for melanocytes to produce melanin from the amino acid ...
The melanocyte-stimulating hormones, known collectively as MSH, also known as melanotropins or intermedins, are a family of peptide hormones and neuropeptides consisting of α-melanocyte-stimulating hormone (α-MSH), β-melanocyte-stimulating hormone (β-MSH), and γ-melanocyte-stimulating hormone (γ-MSH) that are produced by cells in the pars intermedia of the anterior lobe of the pituitary ...
Melanin is produced within the skin in cells called melanocytes and it is the main determinant of the skin color of darker-skin humans. The skin color of people with light skin is determined mainly by the bluish-white connective tissue under the dermis and by the hemoglobin circulating in the veins of the dermis.
It’s also a powerful treatment for melasma since it inhibits the production of pigment in the skin and the transfer of melanin between cells, meaning it can reduce and help prevent dark spots ...
Melanin [22] is a class of compounds that serves as a pigment with different structures responsible for dark, tan, yellowish / reddish pigments in marine animals. It is produced as the amino acid tyrosine is converted into melanin, which is found in the skin, hair, and eyes. Derived from aerobic oxidation of phenols, they are polymers.
α-Melanocyte-stimulating hormone (α-MSH) is an endogenous peptide hormone and neuropeptide of the melanocortin family, with a tridecapeptide structure and the amino acid sequence Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH 2.
Melanin is a chromophore that exists in the human epidermal layer of skin responsible for protection from harmful UV radiation. When melanocytes are stimulated by solar radiation, melanin is produced. [7] Melanin is one of the major absorbers of light in some biological tissue (although its contribution is smaller than other components).