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  2. Urinary anti-infective agent - Wikipedia

    en.wikipedia.org/wiki/Urinary_anti-infective_agent

    It is important to note that the dosage of antibiotics used in children is typically weight-dependent. Generally, oral or parenteral cephalosporins are recommended as the first-line agent for children older than two months. [45] [46] Second-line therapy should be considered for patients who have poor response to first-line treatment ...

  3. Sulopenem/probenecid - Wikipedia

    en.wikipedia.org/wiki/Sulopenem/probenecid

    Trial 2 (NCT03354598) was a noninferiority trial in which 1660 adult women with uncomplicated urinary tract infections were randomized and treated. [2] Sulopenem/probenecid demonstrated efficacy in participants with ciprofloxacin-resistant pathogens with a composite response rate of 48% compared to a composite response rate of 33% in the ...

  4. Mecillinam - Wikipedia

    en.wikipedia.org/wiki/Mecillinam

    Mecillinam is used in the treatment of infections due to susceptible gram-negative bacteria, especially urinary tract infections which are most commonly caused by Escherichia coli. [5] Mecillinam is active against most pathogenic Gram-negative bacteria, except Pseudomonas aeruginosa and some species of Proteus. [6]

  5. Trimethoprim - Wikipedia

    en.wikipedia.org/wiki/Trimethoprim

    It is generally not recommended for the treatment of anaerobic infections such as Clostridioides difficile colitis (the leading cause of antibiotic-induced diarrhea). [7] Trimethoprim has been used in trials to treat retinitis. [8] Resistance to trimethoprim is increasing, but it is still a first-line antibiotic in many countries. [9]

  6. Pivmecillinam - Wikipedia

    en.wikipedia.org/wiki/Pivmecillinam

    Pivmecillinam , or amdinocillin pivoxil , sold under the brand name Selexid and Pivya among others, is an orally active prodrug of mecillinam, an extended-spectrum penicillin antibiotic. Pivmecillinam is the pivaloyloxymethyl ester of mecillinam. The most common side effects include nausea and diarrhea. [3]

  7. Fosfomycin - Wikipedia

    en.wikipedia.org/wiki/Fosfomycin

    Fosfomycin can be used as an efficacious treatment for both UTIs and complicated UTIs including acute pyelonephritis. The standard regimen for complicated UTIs is an oral 3 g dose administered once every 48 or 72 hours for a total of 3 doses or a 6 g dose every 8 hours for 7–14 days when fosfomycin is given in IV form. [18]

  8. Cefixime - Wikipedia

    en.wikipedia.org/wiki/Cefixime

    Cefixime is a broad spectrum cephalosporin antibiotic and is commonly used to treat bacterial infections of the ear, urinary tract, and upper respiratory tract. The following represents MIC susceptibility data for a few medically significant microorganisms: [15] Escherichia coli: 0.015 μg/mL – 4 μg/mL

  9. Colistin - Wikipedia

    en.wikipedia.org/wiki/Colistin

    Colistin-resistant E. coli was identified in the United States in May 2016. [44] A recent review from 2016 to 2021 fount that E. coli is the dominant species harbouring mcr genes. Plasmid - mediated colistin resistance is also conferred upon other species that carry different genes resistant to antibiotics.

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