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  2. Discovery and development of gastrointestinal lipase inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    Orlistat has a few adverse effects. Most reported side effects are gastrointestinal; including liquid stools, steatorrhea and abdominal pain. More severe and serious are interactions between orlistat and anticoagulants when given in combination. It can increase INR which can lead to insufficient anticoagulant treatment and bleeding. [12]

  3. Lipase inhibitors - Wikipedia

    en.wikipedia.org/wiki/Lipase_inhibitors

    Lipase inhibitors can be found naturally in plants and can also be produced as pharmaceutical drugs.Some lipase inhibitors have been identified in Panax ginseng. [5] [6] Some active compounds with chalcone scaffold found in Glycyrrhiza glabra, Cassia mimosoides, Glycyrrhiza uralensis, Boesenbergia rotunda, apples and Morus alba also had strong effect against lipase.

  4. Alpha-glucosidase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Alpha-glucosidase_inhibitor

    In the colon, bacteria will digest the complex carbohydrates, thereby causing gastrointestinal side effects such as flatulence and diarrhea. Since these effects are dose-related, it is generally advised to start with a low dose and gradually increase the dose to the desired amount. Pneumatosis cystoides intestinalis is another reported side ...

  5. Pancreatic enzymes (medication) - Wikipedia

    en.wikipedia.org/wiki/Pancreatic_enzymes...

    Common side effects include vomiting, abdominal pain, constipation, and diarrhea. [3] Other side effects include perianal irritation and high blood uric acid. [5] The enzymes are from pigs. [5] Use is believed to be safe during pregnancy. [5] The components are digestive enzymes similar to those normally produced by the human pancreas. [6]

  6. Billionaire entrepreneur and top adviser to President-elect Donald Trump, Elon Musk, touted that he has reaped the benefits of a controversial class of weight-loss drugs, after fellow top Trump ...

  7. Eluxadoline - Wikipedia

    en.wikipedia.org/wiki/Eluxadoline

    Eluxadoline is a μ-and κ-opioid receptor agonist and δ-opioid receptor antagonist [12] that acts locally in the enteric nervous system, possibly decreasing adverse effects on the central nervous system. [13] [14]

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