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In addition, whereas bicalutamide monotherapy can increase testosterone levels by up to 2-fold in men, [64] [76] the medication does not increase testosterone levels in women. [ 77 ] [ 78 ] [ 79 ] For these reasons, much lower dosages of bicalutamide (e.g., 25 mg/day in the hirsutism studies) may be used in women with significant antiandrogenic ...
If testosterone levels drop below normal values, libido (sexual drive) is reduced, which can lead to the development of erectile dysfunction (a condition in which the penis is not able to get or stay erect). [14] This can indirectly affect fertility as well. In addition, testosterone is important in muscle mass formation.
As of 2016, the International Society for the Study of the Aging Male defines late-onset hypogonadism as a series of symptoms in older adults related to testosterone deficiency that combines features of both primary and secondary hypogonadism; the European Male Aging Study (a prospective study of ~3000 men) [10] defined the condition by the presence of at least three sexual symptoms (e.g ...
Testosterone has been used to successfully treat undervirilization in some [17] but not all [84] men with PAIS, despite having supraphysiological levels of testosterone to start with. [ 17 ] [ 85 ] Treatment options include transdermal gels or patches, oral or injectable testosterone undecanoate , other injectable testosterone esters ...
The most important risk factors for osteoporosis are advanced age (in both men and women) and female sex; estrogen deficiency following menopause or surgical removal of the ovaries is correlated with a rapid reduction in bone mineral density, while in men, a decrease in testosterone levels has a comparable (but less pronounced) effect. [33] [34]
As of the market close on Monday, shares were up nearly 19% year to date, trailing behind the S&P 500's 25% gain. The earnings breakdown Here's what Best Buy posted for the third quarter, compared ...
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