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According to a 2015 review article, Lewis lung carcinoma is the only reproducable syngeneic lung cancer model, meaning that it is the only reproducible lung cancer model that utilizes a transplant that is immunologically compatible. Syngeneic models have proven to be useful in predicting clinical benefit of therapy in preclinical experiments.
A genetically modified mouse, genetically engineered mouse model (GEMM) [1] or transgenic mouse is a mouse (Mus musculus) that has had its genome altered through the use of genetic engineering techniques. Genetically modified mice are commonly used for research or as animal models of human diseases and are also used for research on genes.
MMTV-PyMT is the model of breast cancer metastasis, in which MMTV-LTR is used to drive the expression of mammary gland specific polyomavirus middle T-antigen, leading to a rapid development of highly metastatic tumors. [45] MMTV-PyMT is the most commonly used model for the study of mammary tumor progression and metastasis.
It is the most widely used "genetic background" for genetically modified mice for use as models of human disease. They are the most widely used and best-selling mouse strain due to the availability of congenic strains, easy breeding, and robustness. [1] The median lifespan of C57BL/6 mice is 27–29 months and the maximum lifespan is about 36 ...
Microsoft Translator or Bing Translator is a multilingual machine translation cloud service provided by Microsoft.Microsoft Translator is a part of Microsoft Cognitive Services [1] and integrated across multiple consumer, developer, and enterprise products, including Bing, Microsoft Office, SharePoint, Microsoft Edge, Microsoft Lync, Yammer, Skype Translator, Visual Studio, and Microsoft ...
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This word refers to a wedge-shaped block that's placed against a wheel to prevent it from moving. It's commonly used on larger vehicles. OK, that's it for hints—I don't want to totally give it ...
Refers to words/phrases that are very informal. In some cases, they are vulgar or offensive. OK, that's it for hints—I don't want to totally give it away before revealing the answer!