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Lisinopril works by inhibiting the renin–angiotensin–aldosterone system. [7] Lisinopril was patented in 1978 and approved for medical use in the United States in 1987. [7] [11] It is available as a generic medication. [7] In 2022, it was the third most commonly prescribed medication in the United States, with more than 82 million prescriptions.
Lisinopril/hydrochlorothiazide, sold under the brand name Zestoretic among others, is a fixed-dose combination medication used for the treatment of high blood pressure (hypertension). [2] It contains lisinopril , an ACE inhibitor , and hydrochlorothiazide , a diuretic .
This list contains 1200 recommendations for 591 drugs and 103 therapeutic equivalents. [ 20 ] A separate list for children up to 12 years of age, known as the WHO Model List of Essential Medicines for Children (EMLc), was created in 2007 and is in its 9th edition.
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Chlorthalidone is the thiazide drug that is most strongly supported by the evidence as providing a mortality benefit; in the ALLHAT study, a chlorthalidone dose of 12.5 mg was used, with titration up to 25 mg for those subjects who did not achieve blood pressure control at 12.5 mg. Chlorthalidone has repeatedly been found to have a stronger ...
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