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The Cancer Genome Atlas (TCGA) is a project to catalogue the genomic alterations responsible for cancer using genome sequencing and bioinformatics. [1] [2] The overarching goal was to apply high-throughput genome analysis techniques to improve the ability to diagnose, treat, and prevent cancer through a better understanding of the genetic basis of the disease.
Modern fate mapping began in 1929 when Walter Vogt invented a process which involved marking a specific region of a developing embryo using a dyed agar chip and tracking the cells through gastrulation. [3] To achieve this experiment, Vogt allowed dye and agar to dry on a microscope plate, and placed small pieces onto specific embryo locations.
Turajlic is the Chief Clinical Investigator and Chief Scientific Investigator for the TRACERx Renal, which aims to map how kidney cancer evolves over time. [3] By developing techniques to analyse a cancer's history, her work has revealed that kidney cancers follow a set number of evolutionary paths, each with its own distinct set of genetic ...
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Pan-cancer studies aim to detect the genes whose mutation is conducive to oncogenesis, as well as recurrent genomic events or aberrations between different tumors.For these studies, it is necessary to standardize the data between multiple platforms, establishing criteria between different researchers to work on the data and present the results.
The goals of the project are to help sequence and catalog different cancer genomes. Beyond just sequencing the project's internal partners each have different areas of focus that will assist in the project's overall goal of determining unique ways for early detection of cancer, better prevention, and improved treatment for patients.
The Cancer Imaging Archive (TCIA) is an open-access database of medical images for cancer research. The site is funded by the National Cancer Institute's (NCI) Cancer Imaging Program, and the contract is operated by the University of Arkansas for Medical Sciences. Data within the archive is organized into collections which typically share a ...
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