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A549 cells are adenocarcinomic human alveolar basal epithelial cells, and constitute a cell line that was first developed in 1972 by D. J. Giard, et al. through the removal and culturing of cancerous lung tissue in the explanted tumor of a 58-year-old caucasian male. [1]
There are several examples of immortalised cell lines, each with different properties. Most immortalised cell lines are classified by the cell type they originated from or are most similar to biologically 3T3 cells – a mouse fibroblast cell line derived from a spontaneous mutation in cultured mouse embryo tissue.
This list, containing 488 cell lines, was last updated on 1 December 2016. [c] Cellosaurus also is maintaining a list of "problematic" cell lines. [6] The list is dynamically generated from all cell lines in the database with a comment containing the dedicated words "Problematic cell line". As of 17 January 2017, the list contains 757 entries.
A549: Human: Lung: Human alveolar adenocarcinoma cell line - A549 cultured by MLM at different time points and cell numbers. [8] Immunohistochemistry (IHC) reveals epithelial markers on A549 after culturing in 3D with the MLM. Type II alveolar [8] Primary: Human: Lung: Human tracheal smooth muscle cells (HTSMCs) [8] Primary: Human: Lung
Some research shows that personality traits might play a role in someone’s likelihood of developing PTSD after a trauma. For example, one study found that kids who react strongly to new things ...
This post may contain links from our sponsors and affiliates, and Flywheel Publishing may receive compensation for actions taken through them. On January 20, 2025, Donald Trump will be inaugurated ...
A549 cells share the same characteristics with the alveolar type II cells. This are type II pneumocytes crucial for lung homeostasis, and regeneration upon damage. For research purposes to unravel different molecular mechanisms leading to lung diseases, A549 cells serves as a good model to which translational research can be relied upon.
The list included Trump's political allies Roger Stone and Paul Manafort, who were criminally charged in the Mueller investigation, and Jared Kushner's father, Charles Kushner, ...