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Gabapentin, sold under the trade name Neurontin, is used to treat neuropathic pain in horses. It may be given orally or intravenously, although oral bioavailability is fairly poor (~16%), and it can produce sedation and increased drinking. [81] Gabapentin has been used for femoral neuropathy following surgery, [82] laminitis, and headshaking in ...
Pain is the most common cause of lameness in the horse. [2] It is usually the result of trauma or orthopedic disease, but other causes such as metabolic dysfunction, circulatory disease, and infection can also cause pain and subsequent lameness.
Isoxsuprine (used as isoxsuprine hydrochloride) is a drug used as a vasodilator [4] in humans (under the trade name Duvadilan) and equines. Isoxsuprine is a β 2 adrenoreceptor agonist that causes direct relaxation of uterine and vascular smooth muscle via β 2 receptors .
This sometimes leads to static laminitis, particularly if the animal is confined in a stall. [10] A notable example is the 2006 Kentucky Derby winner Barbaro. [11] Transport laminitis sometimes occurs in horses confined in a trailer or other transportation for long periods of time. Historically, the most extreme instances were of horses shipped ...
Heel pain is very common in horses with navicular syndrome. Lameness may begin as mild and intermittent, and progress to severe. This may be due to strain and inflammation of the ligaments supporting the navicular bone, reduced blood flow and increased pressure within the hoof, damage to the navicular bursa or DDF tendon, or from cartilage erosion.
Pituitary pars intermedia dysfunction (PPID), or equine Cushing's disease, is an endocrine disease affecting the pituitary gland of horses. It is most commonly seen in older animals, [ 1 ] and is classically associated with the formation of a long, wavy coat ( hirsutism ) and chronic laminitis .
Horses are best managed by only allowing short grazing periods—less than 1 hour since they can rapidly ingest grass, [18] or confining them to a limited turn-out area or by use of a grazing muzzle. Horses with severe IR, that have recurrent laminitis, are not recommended to return to pasture. Hay low in NSC is provided in place of pasture.
Grass sickness, alternatively termed equine dysautonomia, is a rare but predominantly fatal illness in horses. Grass sickness may affect all types of horse, pony and donkey , and has affected some well known horses including the thoroughbred stallions Dubai Millennium , Moorestyle and Mister Baileys .