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[14] [12] However, all NSAIDs showed association with structural cardiac defects with usage during the early weeks of pregnancy. When ibuprofen and naproxen are used within the third trimester, there is a significant increase in the risk of premature closure of the ductus arteriosus with primary pulmonary hypertension in the newborn. [ 12 ]
Tocolytics are used in preterm labor, which refers to when a baby is born too early before 37 weeks of pregnancy. As preterm birth represents one of the leading causes of neonatal morbidity and mortality, the goal is to prevent neonatal morbidity and mortality through delaying delivery and increasing gestational age by gaining more time for other management strategies like corticosteroids ...
Abortion doping is a rumoured practice of purposely inducing pregnancy specifically for athletic performance-enhancing benefits, and then aborting the pregnancy. Rumours and allegations began during international sporting events in the mid-twentieth century, and a number of doctors and scientists have repeated claims about it, but it remains unproven, and is often regarded as a myth.
There are health risks to the woman in continuing the pregnancy (e.g. she has pre-eclampsia). Premature rupture of the membranes (PROM); this is when the membranes have ruptured, but labor does not start within a specific amount of time. [2] Premature termination of the pregnancy (abortion). Fetal death in utero and previous history of stillbirth.
If the pregnancy involves twins, a higher dosage of mifepristone may be recommended. [24] Medical abortion performed very early, before the pregnancy can be detected by ultrasound, is just as safe and effective as medical abortion after the pregnancy is detectable by ultrasound. [25]
If fertilization, implantation, and other events necessary for pregnancy occur, increased progestin (i.e., progesterone) levels are essential in maintaining the pregnancy. Blocking the effects of progestins like progesterone is associated with anti-gestational effects, resulting in the interruption of pregnancy maintenance.
The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy.It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk.
Primodos was a hormone-based pregnancy test, produced by Schering AG, and used in the 1960s and 1970s that consisted of two pills that contained norethisterone (as acetate) and ethinylestradiol. [ 1 ] [ 2 ] It detected pregnancy by inducing menstruation in women who were not pregnant.