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Peritoneal dialysis (PD) is a type of dialysis that uses the peritoneum in a person's abdomen as the membrane through which fluid and dissolved substances are exchanged with the blood. [ 1 ] [ 2 ] It is used to remove excess fluid, correct electrolyte problems , and remove toxins in those with kidney failure . [ 3 ]
Dialysis occurs throughout nature and the principles of dialysis have been exploited by humans for thousands of years using natural animal or plant-based membranes. [ 2 ] [ 3 ] [ 4 ] The term dialysis was first routinely used for scientific or medical purposes in the late 1800s and early 1900s, pioneered by the work of Thomas Graham .
In one form of dialysis, called peritoneal dialysis, a glucose solution is sent through a tube into the peritoneal cavity. The fluid is left there for a prescribed amount of time to absorb waste products, and then removed through the tube. The reason for this effect is the high number of arteries and veins in the peritoneal cavity.
Renal replacement therapy includes dialysis (hemodialysis or peritoneal dialysis), hemofiltration, and hemodiafiltration, which are various ways of filtration of blood with or without machines. Renal replacement therapy also includes kidney transplantation , which is the ultimate form of replacement in that the old kidney is replaced by a donor ...
Dialysis is an imperfect treatment to replace kidney function because it does not correct the compromised endocrine functions of the kidney. Dialysis treatments replace some of these functions through diffusion (waste removal) and ultrafiltration (fluid removal). [6] Dialysis uses highly purified (also known as "ultrapure") water. [7]
Hemodialysis, also spelled haemodialysis, or simply dialysis, is a process of filtering the blood of a person whose kidneys are not working normally. This type of dialysis achieves the extracorporeal removal of waste products such as creatinine and urea and free water from the blood when the kidneys are in a state of kidney failure.
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However, only a small portion of dialysis patients use peritoneal dialysis treatment because it requires large amounts of dialysate to be stored and disposed. A healthy individual's kidneys filter blood 24 hours/day, 168 hours/week compared to an individual with end-stage renal disease whose dialysis treatment plan is approximately 12 hours a week.