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Taxus brevifolia, the Pacific yew or western yew, is a species of tree in the yew family Taxaceae native to the Pacific Northwest of North America. It is a small evergreen conifer , thriving in moisture and otherwise tending to take the form of a shrub .
Taxus brevifolia. Chemicals extracted from clippings of Taxus brevifolia (Pacific yew) have been used as the basis for two chemotherapy drugs, docetaxel and paclitaxel. [8] Euphorbia peplus. Contains ingenol mebutate (Picato) which is used to treat skin cancer [9] Maytenus ovatus
Taxine can be found in Taxus species: Taxus cuspidata, T. baccata (English yew), Taxus x media, Taxus canadensis, Taxus floridana, and Taxus brevifolia (Pacific or western yew). All of these species contain taxine in every part of the plant except in the aril , [ citation needed ] the fleshy covering of the seeds (berries).
The Pacific yew (Taxus brevifolia), native to the Pacific Northwest of North America, and the Canada yew (Taxus canadensis) of Eastern and Central North America were the initial sources of paclitaxel or Taxol, a chemotherapeutic drug used in breast and lung cancer treatment and, more recently, in the production of the Taxus drug eluting stent ...
Taxanes are natural and semi-synthetic drugs. The first drug of their class, paclitaxel, was originally extracted from Taxus brevifolia, the Pacific yew. Now this drug and another in this class, docetaxel, are produced semi-synthetically from a chemical found in the bark of another yew tree, Taxus baccata. [56]
They are many-branched, small trees and shrubs.The leaves are evergreen, spirally arranged, often twisted at the base to appear 2-ranked.They are linear to lanceolate, and have pale green or white stomatal bands on the undersides.
This diterpenoid is an important drug in the treatment of cancer but, also expensive because the compound is harvested from a scarce resource, namely the Pacific yew (Taxus brevifolia). Not only is the synthetic reproduction of the compound itself of great commercial and scientific importance, but it also opens the way to paclitaxel derivatives ...
It is most prominently given to any of various coniferous trees and shrubs in the genus Taxus: European yew or common yew (Taxus baccata) Pacific yew or western yew (Taxus brevifolia) Canadian yew (Taxus canadensis) Chinese yew (Taxus chinensis) Japanese yew (Taxus cuspidata) Florida yew (Taxus floridana) Mexican yew (Taxus globosa)