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As per Falkow's original descriptions, the three postulates are: [1] "The phenotype or property under investigation should be associated with pathogenic members of a genus or pathogenic strains of a species. Specific inactivation of the gene(s) associated with the suspected virulence trait should lead to a measurable loss in pathogenicity or ...
Falkow is known as the father of the field of molecular microbial pathogenesis. [1] He formulated molecular Koch's postulates, which have guided the study of the microbial determinants of infectious diseases since the late 1980s. [2] Falkow spent over 50 years uncovering molecular mechanisms of how bacteria cause disease and how to disarm them. [1]
In 1988, microbiologist Stanley Falkow developed a set of three Molecular Koch's postulates for identifying the microbial genes encoding virulence factors. First, the phenotype of a disease symptom must be associated with a specific genotype only found in pathogenic strains. Second, that symptom should not be present when the associated gene is ...
Microbial pathogenesis is a field of microbiology that started at least as early as 1988, with the identification of the triune Falkow's criteria, aka molecular Koch's postulates.
The symposium and these papers provide powerful testimony to the profound impact that Harden McConnell has had in the fields of chemical physics, molecular biophysics, and cellular biophysics. McConnell's influence comes not only from his own impressive publication list, but also from the scores of scientists whose careers he has inspired, by ...
Michael Kasha (December 6, 1920 – June 12, 2013) was an American physical chemist and molecular spectroscopist who was one of the original founders of the Institute of Molecular Biophysics at Florida State University. [3]
Two Indian chemical companies have been indicted for allegedly importing ingredients for the highly addictive opioid fentanyl into the United States and Mexico, the U.S. Department of Justice said ...
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