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Testicular radiation damages the androgen-producing Leydig cells while CNS radiation impairs the hypothalamic-pituitary-gonadal (HPG) axis, reducing gonadotropin production. [9] In prepubescent females, high radiation dose to the pelvic region can also have adverse side effects on fertility.
Radiation-induced lumbar plexopathy (RILP) or radiation-induced lumbosacral plexopathy (RILSP) is nerve damage in the pelvis and lower spine area caused by therapeutic radiation treatments. RILP is a rare side effect of external beam radiation therapy [ 1 ] [ 2 ] [ 3 ] and both interstitial and intracavity brachytherapy radiation implants.
It is one of the most prevalent side effects, affecting about one third of people undergoing pelvic radiation therapy. [ 12 ] [ 13 ] Radiation-induced stenosis can be a late reaction to treatment. Damage to the vaginal epithelium causes abnormal collagen production that leads to atrophy , loss of muscle, decreased blood flow, hypoxia , and ...
Radiation enteropathy is a syndrome that may develop following abdominal or pelvic radiation therapy for cancer. [ 1 ] [ 2 ] Many affected people are cancer survivors who had treatment for cervical cancer or prostate cancer .
Radiation therapy (RT) is in itself painless, but has iatrogenic side effect risks. Many low-dose palliative treatments (for example, radiation therapy to bony metastases) cause minimal or no side effects, although short-term pain flare-up can be experienced in the days following treatment due to oedema compressing nerves in the treated area ...
Pelvic floor muscle therapy is the first line of treatment for urinary incontinence and thus should be considered before more invasive procedures such as surgery. [20] Being able to control the pelvic floor muscles is vital for a well functioning pelvic floor.
Radiation proctitis or radiation proctopathy is a condition characterized by damage to the rectum after exposure to x-rays or other ionizing radiation as a part of radiation therapy. [1] Radiation proctopathy may occur as acute inflammation called "acute radiation proctitis" (and the related radiation colitis) or with chronic changes ...
The use of radiotherapy in colon cancer is not routine due to the sensitivity of the bowels to radiation. [155] Radiation therapy's side effects (and occurrence rates) include acute (27%) and late (17%) dermatological toxicities, acute (14%) and late (27%) gastrointestinal toxicities, [154] and late pelvic radiation disease (1-10%), e.g ...
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