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  2. Atypical ductal hyperplasia - Wikipedia

    en.wikipedia.org/wiki/Atypical_ductal_hyperplasia

    Atypical ductal hyperplasia (ADH) is the term used for a benign lesion of the breast that indicates an increased risk of breast cancer. [1]The name of the entity is descriptive of the lesion; ADH is characterized by cellular proliferation (hyperplasia) within one or two breast ducts and (histomorphologic) architectural abnormalities, i.e. the cells are arranged in an abnormal or atypical way ...

  3. Cytokeratin 5/6 antibodies - Wikipedia

    en.wikipedia.org/wiki/Cytokeratin_5/6_antibodies

    For breast pathology, also in distinguishing usual ductal hyperplasia (UDH) and papillary lesions (having a mosaic-like pattern) from ductal carcinoma in situ, which is usually negative. [1] Cyclin D1 and CK5/6 staining could be used in concert to distinguish between the diagnosis of papilloma (Cyclin D1 < 4.20%, CK 5/6 positive) or papillary ...

  4. Ductal carcinoma in situ - Wikipedia

    en.wikipedia.org/wiki/Ductal_carcinoma_in_situ

    Ductal carcinoma in situ (DCIS), also known as intraductal carcinoma, is a pre-cancerous or non-invasive cancerous lesion of the breast. [ 1 ] [ 2 ] DCIS is classified as Stage 0. [ 3 ] It rarely produces symptoms or a breast lump that can be felt, typically being detected through screening mammography .

  5. Comedocarcinoma - Wikipedia

    en.wikipedia.org/wiki/Comedocarcinoma

    Comedocarcinoma is a kind of breast cancer that demonstrates comedonecrosis, which is the central necrosis [1] of cancer cells within involved ducts. Comedocarcinomas are usually non-infiltrating and intraductal tumors, characterized as a comedo-type, high-grade ductal carcinoma in situ (DCIS).

  6. Usual ductal hyperplasia - Wikipedia

    en.wikipedia.org/wiki/Usual_ductal_hyperplasia

    Usual ductal hyperplasia with small cells that lack atypia. Histopathology of usual ductal hyperplasia (UDH) on H&E stain and immunohistochemistry.As seen on higher magnification H&E stain at left, it has the usual irregular "slit-like" lumina.

  7. Anatomical pathology - Wikipedia

    en.wikipedia.org/wiki/Anatomical_pathology

    Anatomical pathology (Commonwealth) or anatomic pathology (U.S.) is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.

  8. Lobular carcinoma in situ - Wikipedia

    en.wikipedia.org/wiki/Lobular_carcinoma_in_situ

    Lobular neoplasia is considered pre-cancerous, and LCIS is an indicator (marker) for increased risk of developing invasive breast cancer in women. This risk extends more than 20 years. Most of the risk relates to subsequent invasive ductal carcinoma rather than to invasive lobular carcinoma. [4]

  9. Tubular carcinoma - Wikipedia

    en.wikipedia.org/wiki/Tubular_carcinoma

    Pathology [ edit ] Although tubular carcinoma has been considered a special-type tumor, [ a ] recent trend has been to classify it as a low-grade, invasive NOS carcinoma because there is a continuous spectrum from pure tubular carcinomas to mixed NOS [ b ] carcinomas with tubular features, depending on the percentage of the lesion that displays ...