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  2. AURORA trial - Wikipedia

    en.wikipedia.org/wiki/AURORA_trial

    The AURORA trial (A Study to Evaluate the Use of Rosuvastatin in Subjects on Regular Hemodialysis: An Assessment of Survival and Cardiovascular Events) was a randomized, double-blind, placebo-controlled study investigating the use of rosuvastatin in the prevention of cardiovascular disease among patients undergoing chronic hemodialysis.

  3. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    According to the 2015 Cochrane systematic review, atorvastatin showed greater cholesterol-lowering effect in women than in men compared to rosuvastatin. [49] In children, statins are effective at reducing cholesterol levels in those with familial hypercholesterolemia. [50] Their long term safety is, however, unclear.

  4. Rosuvastatin - Wikipedia

    en.wikipedia.org/wiki/Rosuvastatin

    The dose-related magnitude of rosuvastatin on blood lipids was determined in a Cochrane systematic review in 2014. Over the dose range of 1 to 80 mg/day strong linear dose‐related effects were found; total cholesterol was reduced by 22.1% to 44.8%, LDL cholesterol by 31.2% to 61.2%, non-HDL cholesterol by 28.9% to 56.7% and triglycerides by ...

  5. 4 of the Top Prescription Weight Loss Pills & How They Work - AOL

    www.aol.com/4-top-prescription-weight-loss...

    Top Prescription Weight Loss Pills. Anti-obesity medications (AOMs) date back to the 1940s — well before modern regulations from the FDA (U.S. Food and Drug Administration) (FDA) were in place ...

  6. JUPITER trial - Wikipedia

    en.wikipedia.org/wiki/JUPITER_trial

    Reports of serious adverse events within JUPITER were equally distributed between the study's rosuvastatin and placebo arms. There were no significant differences between the treatment groups with respect to muscle pain, muscle weakness, hepatic function, or renal function; however, the researchers noted small but statistically significant increases in the rate of physician-reported diabetes ...

  7. Discovery and development of statins - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    [5] [12] OATP-C is expressed in liver tissue on the basolateral membrane of hepatocytes and is considered to be a potential contributor for the low IC 50 for rosuvastatin in hepatocytes. Of the marketed statins, cerivastatin was the most lipophilic and also had the largest percentage of serious adverse effects due to its ability to inhibit ...

  8. Woman Wants to Call Off Her Wedding After Reaching ... - AOL

    www.aol.com/lifestyle/woman-wants-call-off-her...

    A woman is considering calling off her wedding just months before she's due to walk down the aisle "There's a pit in my stomach I've been trying to ignore.

  9. Why now is still a good time to grow your money in a ... - AOL

    www.aol.com/finance/why-now-still-good-time...

    Despite the recent drop in interest rates, here are six reasons why it’s still a good time for savers to grow their money in a deposit account – even as rates continue to decline. 1. Top five ...