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Cryptococcus neoformans is an encapsulated basidiomycetous yeast [1] belonging to the class Tremellomycetes and an obligate aerobe [2] that can live in both plants and animals. Its teleomorph is a filamentous fungus , formerly referred to Filobasidiella neoformans .
Cryptococcus is a genus of fungi in the family Cryptococcaceae that includes both yeasts and filamentous species. The filamentous, sexual forms or teleomorphs were formerly classified in the genus Filobasidiella, while Cryptococcus was reserved for the yeasts. Most yeast species formerly referred to Cryptococcus have
Data from 2009 estimated that of the almost one million cases of cryptococcal meningitis that occurred worldwide annually, 700,000 occurred in sub-Saharan Africa and 600,000 per year died. [14] Cryptococcosis was rare before the 1970s which saw an increase in at-risk groups such as people with organ transplant or on immunosuppressant ...
Worldwide, the fungi cryptococcus and tuberculosis are leading infectious causes. [3] Immunosuppression (due to a variety of causes) is a major risk factor for the development of chronic infectious meningitis, with Cryptococcus meningitis (which is transmitted by inhalation of fungal spores) being the most common cause of chronic meningitis in ...
Although fungi are eukaryotic, many pathogenic fungi are microorganisms. [1] Approximately 300 fungi are known to be pathogenic to humans; [2] their study is called "medical mycology". Fungal infections are estimated to kill more people than either tuberculosis or malaria—about two million people per year. [3]
Cryptococcus gattii, formerly known as Cryptococcus neoformans var. gattii, is an encapsulated yeast found primarily in tropical and subtropical climates. Its teleomorph is Filobasidiella bacillispora , a filamentous fungus belonging to the class Tremellomycetes .
Fungi are everywhere, but only some cause disease. [13] Fungal infection occurs after spores are either breathed in, come into contact with skin or enter the body through the skin such as via a cut, wound or injection. [3] It is more likely to occur in people with a weak immune system. [14]
Fungi are eukaryotic organisms that can function as pathogens. There are approximately 300 known fungi that are pathogenic to humans, including Candida albicans, which is the most common cause of thrush, and Cryptococcus neoformans, which can cause a severe form of meningitis. [19] Typical fungal spores are 4.7 μm long or smaller. [20]