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Before 1989, the standard treatment for acute melioidosis was a three-drug combination of chloramphenicol, co-trimoxazole, and doxycycline; this regimen is associated with a mortality rate of 80% and is no longer used unless no other alternatives are available. [42]
Burkholderia pseudomallei infection in humans is called melioidosis or Whitmore's disease. It is spread though direct contact with water or soil that holds the bacteria. There have been few cases of transmission of the bacteria perinatally. [40] Its mortality is 20 to 50% even with treatment. [28]
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
Burkholderia is a genus of Pseudomonadota whose pathogenic members include the Burkholderia cepacia complex, which attacks humans and Burkholderia mallei, responsible for glanders, a disease that occurs mostly in horses and related animals; Burkholderia pseudomallei, causative agent of melioidosis; and Burkholderia cepacia, an important pathogen of pulmonary infections in people with cystic ...
A cause of death has been determined for nine monkeys who died over two days in a Hong Kong zoo earlier this week, officials have announced.. The primates at Hong Kong Zoological and Botanical ...
Due to the high mortality rate in humans and the small number of organisms required to establish infection, B. mallei is regarded as a potential biological warfare or bioterrorism agent, as is the closely related organism, B. pseudomallei, the causative agent of melioidosis.
Other teams are dealing with injuries to key players. It's often not the best team that's standing at the end, but the one that was healthiest going into the playoffs. Mahomes has a mild high ...
In epidemiology, case fatality rate (CFR) – or sometimes more accurately case-fatality risk – is the proportion of people who have been diagnosed with a certain disease and end up dying of it. Unlike a disease's mortality rate, the CFR does not take into account the time period between disease onset and death. A CFR is generally expressed ...