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Only the Wolff–Chaikoff effect is helpful to prevent the thyroid from uptaking radioactive iodine in the case of nuclear emergencies. Therefore, "plummering" with high-dose iodine is only effective in a short time window after the release of radionuclides. [15] Wrong timing of iodine use may even increase the risk by triggering the Plummer ...
Unlike the Wolff–Chaikoff effect, the Plummer effect does not prevent the thyroid from taking up radioactive iodine, e.g. in the case of nuclear emergencies.Therefore, "plummering" with high-dose iodine is only effective in a short time window after the release of radionuclides. [9]
Radioactive iodine (iodine-131) alone can potentially worsen thyrotoxicosis in the first few days after treatment. One side effect of treatment is an initial period of a few days of increased hyperthyroid symptoms. This occurs because when the radioactive iodine destroys the thyroid cells, they can release thyroid hormone into the blood stream.
Administering the radioactive isotope causes the thyroid to take in the lethal iodine and quickly radiation destroys it. [12] Typically overproduction of thyroxine using radio-iodine is blocked with one dose. The drawback to this treatment is the thyroid gland is completely destroyed and patients often develop hypothyroidism. Some do so only a ...
Potassium iodide is a chemical compound, medication, and dietary supplement. [4] [5] It is a medication used for treating hyperthyroidism, in radiation emergencies, and for protecting the thyroid gland when certain types of radiopharmaceuticals are used. [6]
“Hypothyroidism is actually quite common and tends to increase with age,” says Dr. Erik Alexander, MD, the chief of the thyroid section at Brigham and Women's Hospital and professor of ...
Radiation-induced thyroiditis is a form of painful, acute thyroiditis resulting from radioactive therapy to treat hyperthyroidism or from radiation to treat head and neck cancer or lymphoma. It affects 1% of those who have received radioactive iodine (I-131) therapy for Graves' Disease , typically presenting between 5 and 10 days after the ...
People who have Graves disease, toxic multinodular goiter, or various types of thyroid adenoma are also at risk of the Jod-Basedow effect when receiving iodine, because the thyroid will then not respond to the negative feedback from increased thyroid hormones. The source of iodine may be from the diet, administration of iodinated contrast for ...
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